Methodology to improve epidermal barrier homeostasis: How to accelerate the barrier recovery?
نویسندگان
چکیده
منابع مشابه
Physical and Chemical Factors that Improve Epidermal Permeability Barrier Homeostasis
For terrestrial creatures, the water-impermeable barrier function of the skin is essential to maintain life in the face of environmental dryness. Stratum corneum, which plays a crucial role in the barrier function, is composed of two components, i.e., protein-rich nonviable cells and intercellular lipid domains. When the barrier function is damaged by a surfactant, organic solvent or tape strip...
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The permeability barrier is required for terrestrial life and is localized to the stratum corneum, where extracellular lipid membranes inhibit water movement. The lipids that constitute the extracellular matrix have a unique composition and are 50% ceramides, 25% cholesterol, and 15% free fatty acids. Essential fatty acid deficiency results in abnormalities in stratum corneum structure function...
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Two families of G protein-coupled receptors of the neurotransmitter dopamine, i.e., dopamine 1-like family (D1-like receptor) and dopamine 2-like family (D2-like receptor), show dopaminergic activity in nerve cells. The D2-like receptor family, composed of D2, D3, and D4 receptors, downregulates the intracellular cAMP signaling pathway, and dopamine receptor agonists reduce the cAMP level in ne...
متن کاملEpidermal Permeability Barrier Recovery Is Delayed in Vitiligo-Involved Sites
Background/Objectives: Prior studies have demonstrated that both the skin surface pH and epidermal permeability barrier function vary with skin pigmentation types. Although melanin deficiency is the main feature of vitiligo, alterations in cutaneous biophysical properties in vitiligo have not yet been well defined. In the present study, stratum corneum (SC) hydration, the skin surface pH and ep...
متن کاملEpidermal permeability barrier recovery is delayed in vitiligo-involved sites.
BACKGROUND/OBJECTIVES Prior studies have demonstrated that both the skin surface pH and epidermal permeability barrier function vary with skin pigmentation types. Although melanin deficiency is the main feature of vitiligo, alterations in cutaneous biophysical properties in vitiligo have not yet been well defined. In the present study, stratum corneum (SC) hydration, the skin surface pH and epi...
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ژورنال
عنوان ژورنال: International Journal of Cosmetic Science
سال: 2009
ISSN: 0142-5463,1468-2494
DOI: 10.1111/j.1468-2494.2008.00487.x